RNAi Mechanism : RNA interference phenomena in cell
Introduction: Here is an amazing topic in our RNA science and technology that is RNA interference and gene silencing .
RNAi mechanism: The whole phenomena is performed inside a cell which targets to silence mRNA Strand and break it down .
Where this function is found ?
The function of RNA interference is found in both Prokaryotic and eukaryotic cells .
# The discoverer of RNA interference is Andrew Fine and Craig Mello .
Here we just briefly study the basic function and future application of RNA interference. It has a massive potential to make a lots of changes in human life.
Lets begin ....
The basically the RNA interference actual goal is to hamper the protein synthesis . We know RNA is single stranded but any how or by any chance Virus produce a double stranded RNA it could be very specific target side to produce RNAi .
It leads to produce Si RNA ,Sh RNA ,Mi RNA.
Here Dicer protein helps trim dsRna to form Si RNA ,Mi RNa ,Sh RNA .
FULL FORM : Si RNA- Small interfering RNA
Sh RNA- Short hairpin RNA
Mi RNA- Micro RNA
These three types of RNA lead to gene silencing by the mixing or combination of RISC ( RNA induced Silencing complex) and stop the protein synthesis.
RISC enzyme is produced by some protein like Slicer ,Argonaut etc ....
Application of RNA interference - If in cell's synthesis protein is not proper made or if it produce malfunctioning protein in cell we even can block the synthesis of protein by this process to make the cell functional .
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