RNAi Mechanism : RNA interference phenomena in cell

Introduction: Here is an amazing topic in our RNA science and technology that is RNA interference and gene silencing .


RNAi mechanism: The whole phenomena is performed inside a cell which targets to silence mRNA Strand and break it down .





Where this function is found ? 

The function of RNA interference is found in both  Prokaryotic and  eukaryotic cells .

# The discoverer of RNA interference is Andrew Fine  and Craig Mello .

Here we just briefly study the basic function and future application of RNA interference. It has a massive potential to make a lots of changes in human life.

Lets begin ....







The basically the RNA interference actual goal is to hamper the protein synthesis . We know RNA is single stranded but any how or by any chance Virus produce a double stranded RNA it could be  very specific target side to produce RNAi .



It leads to produce Si RNA ,Sh RNA ,Mi RNA.
Here Dicer protein helps trim dsRna to form Si RNA ,Mi RNa ,Sh RNA .

FULL FORM : Si RNA- Small interfering RNA
                         Sh RNA- Short hairpin RNA
                         Mi RNA- Micro RNA 
These three types of RNA lead to gene silencing by the mixing or combination of RISC ( RNA induced Silencing complex) and stop the protein  synthesis.
RISC enzyme is produced by some protein like Slicer ,Argonaut etc ....

Now you have learned the basic phenomena if you want to learn the more details pls comment.

Application of RNA interference - If in cell's synthesis protein is not proper made or if it produce malfunctioning protein in cell we even can block the synthesis of protein by this process to make the cell functional .




 

Comments

Popular posts from this blog

Recombinant DNA technology ( Alpha complementation and Blue white screening)

Marine Life

Mechanism of Vesicles Docking and Fusion