Mechanism of Vesicles Docking and Fusion
Abstract: Analysis of Biochemical and Genetics study reveal a molecular mechanism which is selectively cargo molecule transport between donor and target compartments . Different membrane proteins participate in vesicular fusion . #We will discuss about some membrane proteins which participate in vesicles docking and fusion . Protein involved in vesicle docking 1: SNAREs protein: Complimentary sets of vesicles SNAREs(v-SNARE) and target membrane (t-SNARE) contribute to the selectivity of transport vesicle docking and fusion. v-SNARE: During the budding of transport vesicles it is packaged together with coat protein from donor membrane and then bind to complementary t-SNARE in target membrane. t-SNARE: After the fusion t-SNARE Mechanism and v-SNARE make tight co...
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